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Transgenic mice overexpressing miR-137 in the brain show schizophrenia-associated behavioral deficits and transcriptome profiles

Schizophrenia is a psychiatric disorder characterized by positive and negative symptoms and cognitive deficits. The exact cause of schizophrenia is still unknown, but substantial evidence indicates that it has a genetic component. Genome wide association studies demonstrate variants within miR-137 h...

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Detalles Bibliográficos
Autores principales: Arakawa, Yuuichi, Yokoyama, Kazumasa, Tasaki, Shinya, Kato, Junichi, Nakashima, Kosuke, Takeyama, Michiyasu, Nakatani, Atsushi, Suzuki, Motohisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6667145/
https://www.ncbi.nlm.nih.gov/pubmed/31361772
http://dx.doi.org/10.1371/journal.pone.0220389