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Transgenic mice overexpressing miR-137 in the brain show schizophrenia-associated behavioral deficits and transcriptome profiles
Schizophrenia is a psychiatric disorder characterized by positive and negative symptoms and cognitive deficits. The exact cause of schizophrenia is still unknown, but substantial evidence indicates that it has a genetic component. Genome wide association studies demonstrate variants within miR-137 h...
Autores principales: | Arakawa, Yuuichi, Yokoyama, Kazumasa, Tasaki, Shinya, Kato, Junichi, Nakashima, Kosuke, Takeyama, Michiyasu, Nakatani, Atsushi, Suzuki, Motohisa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6667145/ https://www.ncbi.nlm.nih.gov/pubmed/31361772 http://dx.doi.org/10.1371/journal.pone.0220389 |
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