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TET1 regulates fibroblast growth factor 8 transcription in gonadotropin releasing hormone neurons

Fibroblast growth factor 8 (FGF8) is a potent morphogen that regulates the ontogenesis of gonadotropin-releasing hormone (GnRH) neurons, which control the hypothalamus-pituitary-gonadal (HPG) axis, and therefore reproductive success. Indeed, FGF8 and FGFR1 deficiency severely compromises vertebrate...

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Detalles Bibliográficos
Autores principales: Linscott, Megan L., Chung, Wilson C. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6667164/
https://www.ncbi.nlm.nih.gov/pubmed/31361780
http://dx.doi.org/10.1371/journal.pone.0220530