Antitumor activity of novel pyrazole-based small molecular inhibitors of the STAT3 pathway in patient derived high grade glioma cells

Abnormal activation of signal transducer and activator of transcription 3 (STAT3) transcription factor has been observed in many human cancers with roles in tumor initiation, progression, drug resistance, angiogenesis and immunosuppression. STAT3 is constitutively activated in a variety of cancers i...

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Detalles Bibliográficos
Autores principales: Zhang, Liang, Peterson, Timothy E., Lu, Victor M., Parney, Ian F., Daniels, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6667205/
https://www.ncbi.nlm.nih.gov/pubmed/31361777
http://dx.doi.org/10.1371/journal.pone.0220569

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6667205/
https://www.ncbi.nlm.nih.gov/pubmed/31361777
http://dx.doi.org/10.1371/journal.pone.0220569

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