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Antitumor activity of novel pyrazole-based small molecular inhibitors of the STAT3 pathway in patient derived high grade glioma cells

Abnormal activation of signal transducer and activator of transcription 3 (STAT3) transcription factor has been observed in many human cancers with roles in tumor initiation, progression, drug resistance, angiogenesis and immunosuppression. STAT3 is constitutively activated in a variety of cancers i...

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Detalles Bibliográficos
Autores principales:	Zhang, Liang, Peterson, Timothy E., Lu, Victor M., Parney, Ian F., Daniels, David J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6667205/ https://www.ncbi.nlm.nih.gov/pubmed/31361777 http://dx.doi.org/10.1371/journal.pone.0220569

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