PathwayMatcher: proteoform-centric network construction enables fine-granularity multiomics pathway mapping

BACKGROUND: Mapping biomedical data to functional knowledge is an essential task in bioinformatics and can be achieved by querying identifiers (e.g., gene sets) in pathway knowledge bases. However, the isoform and posttranslational modification states of proteins are lost when converting input and p...

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Detalles Bibliográficos
Autores principales: Sánchez, Luis Francisco Hernández, Burger, Bram, Horro, Carlos, Fabregat, Antonio, Johansson, Stefan, Njølstad, Pål Rasmus, Barsnes, Harald, Hermjakob, Henning, Vaudel, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Technical Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6667378/
https://www.ncbi.nlm.nih.gov/pubmed/31363752
http://dx.doi.org/10.1093/gigascience/giz088

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6667378/
https://www.ncbi.nlm.nih.gov/pubmed/31363752
http://dx.doi.org/10.1093/gigascience/giz088

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