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PathwayMatcher: proteoform-centric network construction enables fine-granularity multiomics pathway mapping
BACKGROUND: Mapping biomedical data to functional knowledge is an essential task in bioinformatics and can be achieved by querying identifiers (e.g., gene sets) in pathway knowledge bases. However, the isoform and posttranslational modification states of proteins are lost when converting input and p...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6667378/ https://www.ncbi.nlm.nih.gov/pubmed/31363752 http://dx.doi.org/10.1093/gigascience/giz088 |