Metabolic stress activates an ERK/hnRNPK/DDX3X pathway in pancreatic β cells

OBJECTIVE: Pancreatic β cell failure plays a central role in the development of type 2 diabetes (T2D). While the transcription factors shaping the β cell gene expression program have received much attention, the post-transcriptional controls that are activated in β cells during stress are largely un...

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Detalles Bibliográficos
Autores principales: Good, Austin L., Haemmerle, Matthew W., Oguh, Alexis U., Doliba, Nicolai M., Stoffers, Doris A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6667393/
https://www.ncbi.nlm.nih.gov/pubmed/31178390
http://dx.doi.org/10.1016/j.molmet.2019.05.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6667393/
https://www.ncbi.nlm.nih.gov/pubmed/31178390
http://dx.doi.org/10.1016/j.molmet.2019.05.009

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