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Metabolic stress activates an ERK/hnRNPK/DDX3X pathway in pancreatic β cells
OBJECTIVE: Pancreatic β cell failure plays a central role in the development of type 2 diabetes (T2D). While the transcription factors shaping the β cell gene expression program have received much attention, the post-transcriptional controls that are activated in β cells during stress are largely un...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6667393/ https://www.ncbi.nlm.nih.gov/pubmed/31178390 http://dx.doi.org/10.1016/j.molmet.2019.05.009 |