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Deregulation of TLR4 signaling pathway characterizes Bicuspid Aortic valve syndrome

Bicuspid aortic valve (BAV) disease is recognized to be a syndrome with a complex and multifaceted pathophysiology. Its progression is modulated by diverse evolutionary conserved pathways, such as Notch-1 pathway. Emerging evidence is also highlighting the key role of TLR4 signaling pathway in the a...

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Detalles Bibliográficos
Autores principales: Balistreri, Carmela R., Marullo, Antonino G. M., Madonna, Michele, Cavarretta, Elena, Allegra, Alberto, Cesarini, Valeriana, Iaccarino, Alessandra, Schiavon, Sonia, Peruzzi, Mariangela, Greco, Ernesto, Sciarretta, Sebastiano, Pisano, Calogera, Ruvolo, Giovanni, Torella, Michele, Frati, Giacomo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6667442/
https://www.ncbi.nlm.nih.gov/pubmed/31363123
http://dx.doi.org/10.1038/s41598-019-47412-0