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Neutralized chimeric DNA probe for the improvement of GC-rich RNA detection specificity on the nanowire field-effect transistor

Silicon nanowire (SiNW) field-effect transistors (FETs) is a powerful tool in genetic molecule analysis because of their high sensitivity, short detection time, and label-free detection. In nucleic acid detection, GC-rich nucleic acid sequences form self- and cross-dimers and stem-loop structures, w...

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Detalles Bibliográficos
Autores principales: Chou, Wei-Cheng, Hu, Wen-Pin, Yang, Yuh-Shyong, Chan, Hardy Wai-Hong, Chen, Wen-Yih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6667443/
https://www.ncbi.nlm.nih.gov/pubmed/31363139
http://dx.doi.org/10.1038/s41598-019-47522-9