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Catalytic enantioselective addition of organometallics to unprotected carboxylic acids

Conjugate addition of organometallics to carbonyl based Michael acceptors is a widely used method that allows the building of new carbon-carbon (C-C) bonds and the introduction of chirality in a single step. However, conjugate additions to the simplest Michael acceptors, namely unprotected, unsatura...

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Detalles Bibliográficos
Autores principales: Yan, Xingchen, Harutyunyan, Syuzanna R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6667444/
https://www.ncbi.nlm.nih.gov/pubmed/31363092
http://dx.doi.org/10.1038/s41467-019-11345-z