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Functionalization of Brain Region-specific Spheroids with Isogenic Microglia-like Cells
Current brain spheroids or organoids derived from human induced pluripotent stem cells (hiPSCs) still lack a microglia component, the resident immune cells in the brain. The objective of this study is to engineer brain region-specific organoids from hiPSCs incorporated with isogenic microglia-like c...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6667451/ https://www.ncbi.nlm.nih.gov/pubmed/31363137 http://dx.doi.org/10.1038/s41598-019-47444-6 |