Modification of messenger RNA by 2′-O-methylation regulates gene expression in vivo

Epitranscriptomic modifications of mRNA are important regulators of gene expression. While internal 2′-O-methylation (Nm) has been discovered on mRNA, questions remain about its origin and function in cells and organisms. Here, we show that internal Nm modification can be guided by small nucleolar R...

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Detalles Bibliográficos
Autores principales: Elliott, Brittany A., Ho, Hsiang-Ting, Ranganathan, Srivathsan V., Vangaveti, Sweta, Ilkayeva, Olga, Abou Assi, Hala, Choi, Alex K., Agris, Paul F., Holley, Christopher L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6667457/
https://www.ncbi.nlm.nih.gov/pubmed/31363086
http://dx.doi.org/10.1038/s41467-019-11375-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6667457/
https://www.ncbi.nlm.nih.gov/pubmed/31363086
http://dx.doi.org/10.1038/s41467-019-11375-7

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