Bruton’s tyrosine kinase is at the crossroads of metabolic adaptation in primary malignant human lymphocytes

In this work we explored metabolic aspects of human primary leukemic lymphocytes that hold a potential impact on the treatment of Bruton tyrosine kinase (BTK)-driven diseases. Our results suggest that there is crosstalk between Bruton tyrosine kinase (BTK) signaling and bioenergetic stress responses...

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Detalles Bibliográficos
Autores principales: Sharif-Askari, Bahram, Doyon, Daniel, Paliouras, Miltiadis, Aloyz, Raquel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6667467/
https://www.ncbi.nlm.nih.gov/pubmed/31363127
http://dx.doi.org/10.1038/s41598-019-47305-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6667467/
https://www.ncbi.nlm.nih.gov/pubmed/31363127
http://dx.doi.org/10.1038/s41598-019-47305-2

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