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Bruton’s tyrosine kinase is at the crossroads of metabolic adaptation in primary malignant human lymphocytes
In this work we explored metabolic aspects of human primary leukemic lymphocytes that hold a potential impact on the treatment of Bruton tyrosine kinase (BTK)-driven diseases. Our results suggest that there is crosstalk between Bruton tyrosine kinase (BTK) signaling and bioenergetic stress responses...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6667467/ https://www.ncbi.nlm.nih.gov/pubmed/31363127 http://dx.doi.org/10.1038/s41598-019-47305-2 |