Endogenous IQGAP1 and IQGAP3 do not functionally interact with Ras

The Ras family of small GTPases modulates numerous essential processes. Activating Ras mutations result in hyper-activation of selected signaling cascades, which leads to human diseases. The high frequency of Ras mutations in human malignant neoplasms has led to Ras being a desirable chemotherapeuti...

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Detalles Bibliográficos
Autores principales: Morgan, Chase J., Hedman, Andrew C., Li, Zhigang, Sacks, David B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6667474/
https://www.ncbi.nlm.nih.gov/pubmed/31363101
http://dx.doi.org/10.1038/s41598-019-46677-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6667474/
https://www.ncbi.nlm.nih.gov/pubmed/31363101
http://dx.doi.org/10.1038/s41598-019-46677-9

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