Standard screening methods underreport AAV-mediated transduction and gene editing

Conventional methods to discern adeno-associated virus (AAV) vector transduction patterns are based on high, stable expression of a reporter gene. As a consequence, conventionally described tropisms omit cell types that undergo transient transduction, or have low but undetectable levels of reporter...

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Detalles Bibliográficos
Autores principales: Lang, Jonathan F., Toulmin, Sushila A., Brida, Kasey L., Eisenlohr, Laurence C., Davidson, Beverly L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6667494/
https://www.ncbi.nlm.nih.gov/pubmed/31363095
http://dx.doi.org/10.1038/s41467-019-11321-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6667494/
https://www.ncbi.nlm.nih.gov/pubmed/31363095
http://dx.doi.org/10.1038/s41467-019-11321-7

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