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5-hydroxymethylcytosine Marks Mammalian Origins Acting as a Barrier to Replication
In most mammalian cells, DNA replication occurs once, and only once between cell divisions. Replication initiation is a highly regulated process with redundant mechanisms that prevent errant initiation events. In lower eukaryotes, replication is initiated from a defined consensus sequence, whereas a...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6667497/ https://www.ncbi.nlm.nih.gov/pubmed/31363131 http://dx.doi.org/10.1038/s41598-019-47528-3 |