Interaction of PIAS1 with PRRS virus nucleocapsid protein mediates NF-κB activation and triggers proinflammatory mediators during viral infection

Porcine reproductive and respiratory syndrome virus (PRRSV) activates NF-κB during infection. We examined the ability of all 22 PRRSV genes for NF-κB regulation and determined the nucleocapsid (N) protein as the NF-κB activator. Protein inhibitor of activated STAT1 (signal transducer and activator o...

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Detalles Bibliográficos
Autores principales: Ke, Hanzhong, Lee, Sera, Kim, Jineui, Liu, Hsiao-Ching, Yoo, Dongwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6667501/
https://www.ncbi.nlm.nih.gov/pubmed/31363150
http://dx.doi.org/10.1038/s41598-019-47495-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6667501/
https://www.ncbi.nlm.nih.gov/pubmed/31363150
http://dx.doi.org/10.1038/s41598-019-47495-9

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