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Methylenetetrahydrofolate Reductase Gene C677T and A1298C Polymorphic Sequence Variations Influences the Susceptibility to Chronic Myeloid Leukemia in Kashmiri Population

Background: Methylenetetrahydrofolate reductase (MTHFR) gene is a crucial regulator of folate metabolism and its two prominent polymorphic variants C677T and A1298C lead to decreased MTHFR enzyme activity. Aim of the Study: We planned this case–control study based on numerous studies supporting the...

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Detalles Bibliográficos
Autores principales: Baba, Shahid M., Shah, Zafar A., Javaid, Khushboo, Pandith, Arshad A., Rasool, Javeed, Geelani, Sajad A., Baba, Rafia A., Amin, Shajrul, Mohammad, Gul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6667548/
https://www.ncbi.nlm.nih.gov/pubmed/31396477
http://dx.doi.org/10.3389/fonc.2019.00612