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Using the novel HiBiT tag to label cell surface relaxin receptors for BRET proximity analysis
Relaxin family peptide 1 (RXFP1) is the receptor for relaxin a peptide hormone with important therapeutic potential. Like many G protein‐coupled receptors (GPCRs), RXFP1 has been reported to form homodimers. Given the complex activation mechanism of RXFP1 by relaxin, we wondered whether homodimeriza...
Autores principales: | Hoare, Bradley L., Kocan, Martina, Bruell, Shoni, Scott, Daniel J., Bathgate, Ross A. D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6667744/ https://www.ncbi.nlm.nih.gov/pubmed/31384473 http://dx.doi.org/10.1002/prp2.513 |
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