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Coelomocytes Regulate Starvation-Induced Fat Catabolism and Lifespan Extension through the Lipase LIPL-5 in Caenorhabditis elegans

Dietary restriction is known to extend the lifespan and reduce fat stores in most species tested to date, but the molecular mechanisms linking these events remain unclear. Here, we found that bacterial deprivation of Caenorhabditis elegans leads to lifespan extension with concomitant mobilization of...

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Detalles Bibliográficos
Autores principales: Buis, Alexia, Bellemin, Stéphanie, Goudeau, Jérôme, Monnier, Léa, Loiseau, Nicolas, Guillou, Hervé, Aguilaniu, Hugo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6667774/
https://www.ncbi.nlm.nih.gov/pubmed/31340142
http://dx.doi.org/10.1016/j.celrep.2019.06.064