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Molecular mechanism of Forkhead box M1 inhibition by thiostrepton in breast cancer cells

Breast cancer is the most common type of malignancies in women worldwide, and genotoxic chemotherapeutic drugs are effective by causing DNA damage in cancer cells. However, >90% of patients with metastatic cancer are resistant to chemotherapy. The Forkhead box M1 (FOXM1) transcription factor play...

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Detalles Bibliográficos
Autores principales: Kongsema, Mesayamas, Wongkhieo, Sudtirak, Khongkow, Mattaka, Lam, Eric W.-F., Boonnoy, Phansiri, Vongsangnak, Wanwipa, Wong-Ekkabut, Jirasak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6667886/
https://www.ncbi.nlm.nih.gov/pubmed/31322278
http://dx.doi.org/10.3892/or.2019.7225