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A protocol to transfer a fed‐batch platform process into semi‐perfusion mode: The benefit of automated small‐scale bioreactors compared to shake flasks as scale‐down model
Continuous processes such as perfusion processes can offer advantages compared to fed‐batch or batch processes in bio‐processing: improved product quality (e.g. for labile products), increased product yield, and cost savings. In this work, a semi‐perfusion process was established in shake flasks and...
Autores principales: | Janoschek, Sabrina, Schulze, Markus, Zijlstra, Gerben, Greller, Gerhard, Matuszczyk, Jens |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6667907/ https://www.ncbi.nlm.nih.gov/pubmed/30479066 http://dx.doi.org/10.1002/btpr.2757 |
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