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Does the mouse tail vein injection method provide a good model of lung cancer?

Lung cancer drug development requires screening in animal models. We aimed to develop orthotopic models of human non-small lung cancer using A549 and H3122 cells delivered by tail vein injection. This procedure has been used previously for a mouse lung cancer (Lewis lung carcinoma) and as a model of...

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Detalles Bibliográficos
Autores principales: Shrestha, Nensi, Lateef, Zabeen, Martey, Orleans, Bland, Abigail R., Nimick, Mhairi, Rosengren, Rhonda, Ashton, John C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668049/
https://www.ncbi.nlm.nih.gov/pubmed/31448098
http://dx.doi.org/10.12688/f1000research.17964.1