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Does the mouse tail vein injection method provide a good model of lung cancer?

Lung cancer drug development requires screening in animal models. We aimed to develop orthotopic models of human non-small lung cancer using A549 and H3122 cells delivered by tail vein injection. This procedure has been used previously for a mouse lung cancer (Lewis lung carcinoma) and as a model of...

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Detalles Bibliográficos
Autores principales:	Shrestha, Nensi, Lateef, Zabeen, Martey, Orleans, Bland, Abigail R., Nimick, Mhairi, Rosengren, Rhonda, Ashton, John C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	F1000 Research Limited 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668049/ https://www.ncbi.nlm.nih.gov/pubmed/31448098 http://dx.doi.org/10.12688/f1000research.17964.1

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