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miR-125b-5p inhibits cell proliferation, migration, and invasion in hepatocellular carcinoma via targeting TXNRD1

BACKGROUND: Thioredoxin reductase 1 (TXNRD1) is an antioxidant enzyme reportedly overexpressed in hepatocellular carcinoma (HCC); however, the detailed function and mechanisms of TXNRD1 in HCC remain obscure. In this study, we investigated the miR-125b-5p-specific regulation of TXNRD1 levels and its...

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Detalles Bibliográficos
Autores principales: Hua, Shengni, Quan, Yingyao, Zhan, Meixiao, Liao, Huaxin, Li, Yong, Lu, Ligong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668076/
https://www.ncbi.nlm.nih.gov/pubmed/31384178
http://dx.doi.org/10.1186/s12935-019-0919-6