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The epigenome as a putative target for skin repair: the HDAC inhibitor Trichostatin A modulates myeloid progenitor plasticity and behavior and improves wound healing

BACKGROUND: The molecular pathways that drive bone marrow myeloid progenitors (BMMP) development are very well understood and include a tight controlled multi-stage gene hierarch. Monocytes are versatile cells that display remarkable plasticity and may give rise to specific subsets of macrophages to...

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Detalles Bibliográficos
Autores principales: Cabanel, Mariana, da Costa, Thayse Pinheiro, EL-Cheikh, Marcia Cury, Carneiro, Katia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668089/
https://www.ncbi.nlm.nih.gov/pubmed/31366356
http://dx.doi.org/10.1186/s12967-019-1998-9