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Molecular characterization and functional analysis of the Schistosoma mekongi Ca(2+)-dependent cysteine protease (calpain)

BACKGROUND: Schistosoma mekongi, which causes schistosomiasis in humans, is an important public health issue in Southeast Asia. Treatment with praziquantel is the primary method of control but emergence of praziquantel resistance requires the development of alternative drugs and vaccines. Calcium-de...

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Detalles Bibliográficos
Autores principales: Chaimon, Salisa, Limpanont, Yanin, Reamtong, Onrapak, Ampawong, Sumate, Phuphisut, Orawan, Chusongsang, Phiraphol, Ruangsittichai, Jiraporn, Boonyuen, Usa, Watthanakulpanich, Dorn, O’Donoghue, Anthony J., Caffrey, Conor R., Adisakwattana, Poom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668146/
https://www.ncbi.nlm.nih.gov/pubmed/31362766
http://dx.doi.org/10.1186/s13071-019-3639-9