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Perilesional edema in brain metastases: potential causes and implications for treatment with immune therapy

BACKGROUND: Little is known about tumor-associated vasogenic edema in brain metastasis, yet it causes significant morbidity and mortality. Our purpose was to characterize edema in patients treated with anti-PD-1 and to study potential causes of vessel leakage in humans and in pre-clinical models. ME...

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Detalles Bibliográficos
Autores principales: Tran, Thuy T., Mahajan, Amit, Chiang, Veronica L., Goldberg, Sarah B., Nguyen, Don X., Jilaveanu, Lucia B., Kluger, Harriet M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668163/
https://www.ncbi.nlm.nih.gov/pubmed/31362777
http://dx.doi.org/10.1186/s40425-019-0684-z