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Perilesional edema in brain metastases: potential causes and implications for treatment with immune therapy
BACKGROUND: Little is known about tumor-associated vasogenic edema in brain metastasis, yet it causes significant morbidity and mortality. Our purpose was to characterize edema in patients treated with anti-PD-1 and to study potential causes of vessel leakage in humans and in pre-clinical models. ME...
Autores principales: | Tran, Thuy T., Mahajan, Amit, Chiang, Veronica L., Goldberg, Sarah B., Nguyen, Don X., Jilaveanu, Lucia B., Kluger, Harriet M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668163/ https://www.ncbi.nlm.nih.gov/pubmed/31362777 http://dx.doi.org/10.1186/s40425-019-0684-z |
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