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Tranexamic acid for acute gastrointestinal bleeding (the HALT-IT trial): statistical analysis plan for an international, randomised, double-blind, placebo-controlled trial

BACKGROUND: Acute gastrointestinal (GI) bleeding is an important cause of mortality worldwide. Bleeding can occur from the upper or lower GI tract, with upper GI bleeding accounting for most cases. The main causes include peptic ulcer/erosive mucosal disease, oesophageal varices and malignancy. The...

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Detalles Bibliográficos
Autores principales: Brenner, Amy, Afolabi, Adefemi, Ahmad, Syed Masroor, Arribas, Monica, Chaudhri, Rizwana, Coats, Timothy, Cuzick, Jack, Gilmore, Ian, Hawkey, Christopher, Jairath, Vipul, Javaid, Kiran, Kayani, Aasia, Mutti, Muttiullah, Nadeem, Muhammad Arif, Shakur-Still, Haleema, Stanworth, Simon, Veitch, Andrew, Roberts, Ian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668177/
https://www.ncbi.nlm.nih.gov/pubmed/31362765
http://dx.doi.org/10.1186/s13063-019-3561-7