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Responsiveness to basement membrane extract as a possible trait for tumorigenicity characterization

Immortalized cell lines used to produce vaccines are expected to be described in terms of their tumorigenicity. However, current in vivo tumorigenicity assays can be time-consuming and results can be equivocal, especially for weakly tumorigenic cells. Basement membrane extract (BME) derived from the...

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Detalles Bibliográficos
Autores principales: Murata, Haruhiko, Omeir, Romelda, Tu, Wei, Lanning, Lynda, Phy, Kathryn, Foseh, Gideon, Lewis, Andrew M., Peden, Keith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668224/
https://www.ncbi.nlm.nih.gov/pubmed/31384726
http://dx.doi.org/10.1016/j.jvacx.2019.100004