Targeted acetylcholinesterase-responsive drug carriers with long duration of drug action and reduced hepatotoxicity

PURPOSE: Acetylcholinesterase (AChE) plays a critical role in the transmission of nerve impulse at the cholinergic synapses. Design and synthesis of AChE inhibitors that increase the cholinergic transmission by blocking the degradation of acetylcholine can serve as a strategy for the treatment of AC...

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Detalles Bibliográficos
Autores principales: Lin, Yulong, Wang, Yalin, Lv, Jie, Wang, Nannan, Wang, Jing, Li, Meng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668248/
https://www.ncbi.nlm.nih.gov/pubmed/31440049
http://dx.doi.org/10.2147/IJN.S215404

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668248/
https://www.ncbi.nlm.nih.gov/pubmed/31440049
http://dx.doi.org/10.2147/IJN.S215404

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