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Targeted acetylcholinesterase-responsive drug carriers with long duration of drug action and reduced hepatotoxicity
PURPOSE: Acetylcholinesterase (AChE) plays a critical role in the transmission of nerve impulse at the cholinergic synapses. Design and synthesis of AChE inhibitors that increase the cholinergic transmission by blocking the degradation of acetylcholine can serve as a strategy for the treatment of AC...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Dove
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668248/ https://www.ncbi.nlm.nih.gov/pubmed/31440049 http://dx.doi.org/10.2147/IJN.S215404 |