Influence of CYP3A5 and ABCB1 Polymorphism on Tacrolimus Drug Dosing in South Indian Renal Allograft Recipients

INTRODUCTION: Tacrolimus blood levels are influenced by polymorphisms involving Cytochrome 3A subfamily (CYP3A5) and P-Glycoprotein (ABCB-1) genes. However, their role in transplant outcomes was less studied in South Indian population. We studied the prevalence and impact of these polymorphisms in r...

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Detalles Bibliográficos
Autores principales: Fernando, M. Edwin, Sellappan, Manokaran, Srinivasa Prasad, N. D., Suren, Sujit, Thirumalvalavan, K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668310/
https://www.ncbi.nlm.nih.gov/pubmed/31423060
http://dx.doi.org/10.4103/ijn.IJN_97_18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668310/
https://www.ncbi.nlm.nih.gov/pubmed/31423060
http://dx.doi.org/10.4103/ijn.IJN_97_18

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