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Metastatic cancer cell attachment to endothelium is promoted by endothelial glycocalyx sialic acid degradation

While it is known that cancer cell interactions with vascular endothelial cells (ECs) drive metastatic cancer cell extravasation from blood vessels into secondary tumor sites, the mechanisms of action are still poorly understood. Here, we tested the hypothesis that neuraminidase‐induced degradation...

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Detalles Bibliográficos
Autores principales: Mensah, Solomon A., Harding, Ian C., Zhang, Michelle, Jaeggli, Michael P., Torchilin, Vladimir P., Niedre, Mark J., Ebong, Eno E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668365/
https://www.ncbi.nlm.nih.gov/pubmed/31367063
http://dx.doi.org/10.1002/aic.16634