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ATPase activity of human binding immunoglobulin protein (BiP) variants is enhanced by signal sequence and physiological concentrations of Mn(2+)

B‐cell immunoglobulin binding protein (BiP) is an essential endoplasmic reticulum (ER) chaperone normally found in the ER lumen. However, BiP also has other extracellular and intracellular functions. As it is unclear whether peripheral BiP has a signal and/or ER retention sequence, here we produced...

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Detalles Bibliográficos
Autores principales: Bandla, Sravanthi, Diaz, Suraya, Nasheuer, Heinz Peter, FitzGerald, Una
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668376/
https://www.ncbi.nlm.nih.gov/pubmed/31033254
http://dx.doi.org/10.1002/2211-5463.12645