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Neutralizing monoclonal antibody against Dickkopf2 impairs lung cancer progression via activating NK cells

Adenomatous polyposis coli (APC) and KRAS proto-oncogene (KRAS) mutations frequently co-occur in non-small cell lung cancer. Inactivating APC mutations in colorectal carcinoma has been well characterized, leading to the approaches targeting on dysregulated APC pathway. However, it remains undetermin...

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Detalles Bibliográficos
Autores principales: Shen, Tianli, Chen, Zhengxi, Qiao, Ju, Sun, Xuejun, Xiao, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668384/
https://www.ncbi.nlm.nih.gov/pubmed/31372243
http://dx.doi.org/10.1038/s41420-019-0204-4