Clonal Evolution and Changes in Two AML Patients Detected with A Novel Single-Cell DNA Sequencing Platform

Next-generation sequencing (NGS) is used to detect gene variants in genetically complex cell populations of cancer patient samples. Traditional bulk analysis can only provide average variant allele frequencies of the targeted genes across all sampled cells. It fails to resolve mutational co-occurren...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Liwen, Durruthy-Durruthy, Robert, Eastburn, Dennis J., Pellegrino, Maurizio, Shah, Omid, Meyer, Everett, Zehnder, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668401/
https://www.ncbi.nlm.nih.gov/pubmed/31366893
http://dx.doi.org/10.1038/s41598-019-47297-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668401/
https://www.ncbi.nlm.nih.gov/pubmed/31366893
http://dx.doi.org/10.1038/s41598-019-47297-z

Ejemplares similares