SQSTM1/p62 loss reverses the inhibitory effect of sunitinib on autophagy independent of AMPK signaling

Sunitinib (ST), a multitargeted receptor tyrosine kinase inhibitor, has been demonstrated to be effective for the treatment of renal carcinoma. It has been reported that ST is involved in the mediation of autophagy; however, its regulatory role in the autophagic process remains controversial. Furthe...

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Detalles Bibliográficos
Autores principales: Hou, Bolin, Wang, Gang, Gao, Quan, Wei, Yanjie, Zhang, Caining, Wang, Yange, Huo, Yuqing, Yang, Huaiyi, Jiang, Xuejun, Xi, Zhijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668422/
https://www.ncbi.nlm.nih.gov/pubmed/31366950
http://dx.doi.org/10.1038/s41598-019-47597-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668422/
https://www.ncbi.nlm.nih.gov/pubmed/31366950
http://dx.doi.org/10.1038/s41598-019-47597-4

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