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SQSTM1/p62 loss reverses the inhibitory effect of sunitinib on autophagy independent of AMPK signaling
Sunitinib (ST), a multitargeted receptor tyrosine kinase inhibitor, has been demonstrated to be effective for the treatment of renal carcinoma. It has been reported that ST is involved in the mediation of autophagy; however, its regulatory role in the autophagic process remains controversial. Furthe...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668422/ https://www.ncbi.nlm.nih.gov/pubmed/31366950 http://dx.doi.org/10.1038/s41598-019-47597-4 |