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Comparative Study of Subcutaneous and Orthotopic Mouse Models of Prostate Cancer: Vascular Perfusion, Vasculature Density, Hypoxic Burden and BB2r-Targeting Efficacy

The gastrin-releasing peptide receptor (BB2r) is overexpressed in a variety of cancers including prostate cancer. As a consequence, the development of BB2r-targeted diagnostic/therapeutic radiopharmaceuticals has been widely explored. Both subcutaneous and orthotopic mouse models have been extensive...

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Detalles Bibliográficos
Autores principales: Zhang, Wenting, Fan, Wei, Rachagani, Satyanarayana, Zhou, Zhengyuan, Lele, Subodh M., Batra, Surinder K., Garrison, Jered C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668441/
https://www.ncbi.nlm.nih.gov/pubmed/31366895
http://dx.doi.org/10.1038/s41598-019-47308-z