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GLI1 activation by non-classical pathway integrin α(v)β(3)/ERK1/2 maintains stem cell-like phenotype of multicellular aggregates in gastric cancer peritoneal metastasis

Peritoneal metastasis is one of the most important causes of postoperative death in patients with gastric cancer, and the exact mechanism remains unclear. The proliferation of multicellular aggregates of exfoliated malignant gastric cells in the abdominal cavity is the focus of current research. How...

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Detalles Bibliográficos
Autores principales: Dong, Hui, Liu, Hongchang, Zhou, Wen, Zhang, Fan, Li, Chuan, Chen, Jun, Tan, Chenjun, Tang, Bo, Yu, Peiwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668446/
https://www.ncbi.nlm.nih.gov/pubmed/31366904
http://dx.doi.org/10.1038/s41419-019-1776-x