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Cell-type-specific resolution epigenetics without the need for cell sorting or single-cell biology

High costs and technical limitations of cell sorting and single-cell techniques currently restrict the collection of large-scale, cell-type-specific DNA methylation data. This, in turn, impedes our ability to tackle key biological questions that pertain to variation within a population, such as iden...

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Detalles Bibliográficos
Autores principales: Rahmani, Elior, Schweiger, Regev, Rhead, Brooke, Criswell, Lindsey A., Barcellos, Lisa F., Eskin, Eleazar, Rosset, Saharon, Sankararaman, Sriram, Halperin, Eran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668473/
https://www.ncbi.nlm.nih.gov/pubmed/31366909
http://dx.doi.org/10.1038/s41467-019-11052-9