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Potential population level impact on tuberculosis incidence of using an mRNA expression signature correlate-of-risk test to target tuberculosis preventive therapy

Achieving the WHO End-Tuberculosis (TB) targets requires approaches to prevent progression to TB among individuals with Mycobacterium tuberculosis (M.tb) infection. Effective preventive therapy (PT) exists, but current tests have low specificity for identifying who, among those infected, is at risk...

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Detalles Bibliográficos
Autores principales: Sumner, Tom, Scriba, Thomas J., Penn-Nicholson, Adam, Hatherill, Mark, White, Richard G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668474/
https://www.ncbi.nlm.nih.gov/pubmed/31366947
http://dx.doi.org/10.1038/s41598-019-47645-z