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Potential population level impact on tuberculosis incidence of using an mRNA expression signature correlate-of-risk test to target tuberculosis preventive therapy
Achieving the WHO End-Tuberculosis (TB) targets requires approaches to prevent progression to TB among individuals with Mycobacterium tuberculosis (M.tb) infection. Effective preventive therapy (PT) exists, but current tests have low specificity for identifying who, among those infected, is at risk...
Autores principales: | Sumner, Tom, Scriba, Thomas J., Penn-Nicholson, Adam, Hatherill, Mark, White, Richard G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668474/ https://www.ncbi.nlm.nih.gov/pubmed/31366947 http://dx.doi.org/10.1038/s41598-019-47645-z |
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