HDAC and HMT Inhibitors in Combination with Conventional Therapy: A Novel Treatment Option for Acute Promyelocytic Leukemia

Acute promyelocytic leukemia (APL) is characterized by PML-RARA translocation, which causes the blockage of promyelocyte differentiation. Conventional treatment with Retinoic acid and chemotherapeutics is quite satisfactory. However, there are still patients who relapse or develop resistance to conv...

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Detalles Bibliográficos
Autores principales: Vitkevičienė, Aida, Skiauterytė, Giedrė, Žučenka, Andrius, Stoškus, Mindaugas, Gineikienė, Eglė, Borutinskaitė, Veronika, Griškevičius, Laimonas, Navakauskienė, Rūta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668531/
https://www.ncbi.nlm.nih.gov/pubmed/31396278
http://dx.doi.org/10.1155/2019/6179573

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668531/
https://www.ncbi.nlm.nih.gov/pubmed/31396278
http://dx.doi.org/10.1155/2019/6179573

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