Defibrotide enhances fibrinolysis in human endotoxemia – a randomized, double blind, crossover trial in healthy volunteers

Defibrotide is approved for the treatment of sinusoidal obstruction syndrome after allogeneic stem cell transplantation. The exact mode of action of defibrotide is unclear and human in vivo data are scarce. In this randomized, double blind, crossover trial we included 20 healthy volunteers. Four wer...

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Detalles Bibliográficos
Autores principales: Schoergenhofer, Christian, Buchtele, Nina, Gelbenegger, Georg, Derhaschnig, Ulla, Firbas, Christa, Kovacevic, Katarina D., Schwameis, Michael, Wohlfarth, Philipp, Rabitsch, Werner, Jilma, Bernd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668569/
https://www.ncbi.nlm.nih.gov/pubmed/31366975
http://dx.doi.org/10.1038/s41598-019-47630-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668569/
https://www.ncbi.nlm.nih.gov/pubmed/31366975
http://dx.doi.org/10.1038/s41598-019-47630-6

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